Narcotics/Opiates: CNS and respiratory depressants. Heroin, morphine, codeine, meperidine, propoxyphene, fentanyl, hydrocodone. Euphoria Hypotension Respiratory depression/arrest Nausea Pinpoint pupils Seizures Coma Management: Maintain ABCs. Naloxone (Narcan) antagonizes narcotics (and the users). IV administration may wear off too fast, and wake them up too much. IM dose lasts longer and they awake more slowly.